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        NF-E4 (Acetyl Lys43) rabbit pAb
        
                    ES1124
                    
        
                        
        
                            
        
                                規(guī)格：
                                價(jià)格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        NF-E4 (Acetyl Lys43) rabbit pAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human;Rat;Mouse;
                                        
        
                                                                                
        
                                            Alternative Names:
                                            NFE4; Transcription factor NF-E4
                                        
        
                                                                                
        
                                           Source:
                                           Rabbit
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           -20°C/1 year
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Polyclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1 mg/ml
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           19kD
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           58160
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           Q86UQ8
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           Nucleus .
                                           
                                        
        
                                                                                
        
                                           Background:
                                           The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],
                                           
                                        
        
                                                                        
        
                            
        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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