Product name: |
Cleaved-Cathepsin A 32k (R326) rabbit pAb |
Reactivity: |
Human;Mouse |
Alternative Names: |
CTSA; PPGB; Lysosomal protective protein; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA; Protective protein for beta-galactosidase |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human PPGB. AA range:277-326 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
33kD |
GeneID: |
5476 |
Human Swiss-Prot No: |
P10619 |
Cellular localization: |
Lysosome. |
Background: |
This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015], |