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        CaMKIIα/δ (phospho Thr286) rabbit pAb
        
                    ES7642
                    
        
                        
        
                            
        
                                規(guī)格：
                                價格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    文獻
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        CaMKIIα/δ (phospho Thr286) rabbit pAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human;Mouse;Rat;Pig
                                        
        
                                                                                
        
                                            Alternative Names:
                                            CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II
                                        
        
                                                                                
        
                                           Source:
                                           Rabbit
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           The antiserum was produced against synthesized peptide derived from human CaMK2 around the phosphorylation site of Thr286. AA range:256-305
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           -20°C/1 year
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Polyclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1 mg/ml
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           54kD
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           815/817
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           Q9UQM7/Q13557
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .
                                           
                                        
        
                                                                                
        
                                           Background:
                                           The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
                                           
                                        
        
                                                                        
        
                            
        
                                                        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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