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        CRM1 (Acetyl Lys568) rabbit pAb
        
                    ES1133
                    
        
                        
        
                            
        
                                規(guī)格：
                                價(jià)格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        CRM1 (Acetyl Lys568) rabbit pAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human;Mouse;Rat
                                        
        
                                                                                
        
                                            Alternative Names:
                                            XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
                                        
        
                                                                                
        
                                           Source:
                                           Rabbit
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           -20°C/1 year
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Polyclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1 mg/ml
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           125kD
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           7514
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           O14980
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.
                                           
                                        
        
                                                                                
        
                                           Background:
                                           This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],
                                           
                                        
        
                                                                        
        
                            
        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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