Product name: |
ATF-5 (Acetyl Lys29) rabbit pAb |
Reactivity: |
Human;Mouse;Rat |
Alternative Names: |
ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized Acetyl-peptide derived from human ATF5 around the Acetylation site of Lys29. AA range:1-50 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
30kD |
GeneID: |
22809 |
Human Swiss-Prot No: |
Q9Y2D1 |
Cellular localization: |
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. . |
Background: |
function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2., |