Product name: |
Cleaved-MPO 89k (A49) rabbit pAb |
Reactivity: |
Human;Rat;Mouse; |
Alternative Names: |
MPO; Myeloperoxidase; MPO |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: |
Synthesized peptide derived from Cleaved-MPO 89k (A49) . at AA range: 40-120 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
89kD |
GeneID: |
4353 |
Human Swiss-Prot No: |
P05164 |
Cellular localization: |
Lysosome. |
Background: |
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014], |