Product name: |
Cleaved-MMP-27 (Y99) rabbit pAb |
Reactivity: |
Human;Monkey |
Alternative Names: |
MMP27; Matrix metalloproteinase-27; MMP-27 |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human MMP27. AA range:80-129 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
48kD |
GeneID: |
64066 |
Human Swiss-Prot No: |
Q9H306 |
Cellular localization: |
Endoplasmic reticulum membrane; Peripheral membrane protein . Retained in the endoplasmic reticulum. . |
Background: |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008], |