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        Cleaved-Caspase-2 p18 (G170) rabbit pAb
        
                    ES1016
                    
        
                        
        
                            
        
                                規(guī)格：
                                價格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        Cleaved-Caspase-2 p18 (G170) rabbit pAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human;Mouse;Rat
                                        
        
                                                                                
        
                                            Alternative Names:
                                            CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
                                        
        
                                                                                
        
                                           Source:
                                           Rabbit
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           The antiserum was produced against synthesized peptide derived from human Caspase 2 p18 N-ternal. AA range:151-200
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           -20°C/1 year
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Polyclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1 mg/ml
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           18 or 35kD
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           835
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           P42575
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           nucleus,cytoplasm,mitochondrion,cytosol,membrane,
                                           
                                        
        
                                                                                
        
                                           Background:
                                           This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],
                                           
                                        
        
                                                                        
        
                            
        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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