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        P63-α (3F11) Mouse mAb
        
                    EM1404
                    
        
                        
        
                            
        
                                規(guī)格：
                                價(jià)格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        P63-α (3F11) Mouse mAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human, Rat, Mouse
                                        
        
                                                                                
        
                                           Source:
                                           Mouse
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           WB 1:1,000-2,000?? IHC:1;100-1:200
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           Synthetic Peptide
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Monoclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG1
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1mg/mL
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           50-80kDa
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           8626
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           Q9H3D4
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           Nucleus
                                           
                                        
        
                                                                                
        
                                           Background:
                                           p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .
                                           
                                        
        
                                                                        
        
                            
        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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