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        ATG5 (3C7) Mouse mAb
        
                    EM1374
                    
        
                        
        
                            
        
                                規(guī)格：
                                價(jià)格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        ATG5 (3C7) Mouse mAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human, Mouse, Rat
                                        
        
                                                                                
        
                                            Alternative Names:
                                            APG5, APG5L, ASP, Autophagy protein 5 antibody
                                        
        
                                                                                
        
                                           Source:
                                           Mouse
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           WB? 1:5,000-10,000  IHC 1:100-200
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           Recombinant Protein
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Monoclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG1
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1mg/mL
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           55kDa
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           9494
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           Q9H1Y0
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           Cytoplasm,?Membrane
                                           
                                        
        
                                                                                
        
                                           Background:
                                           Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
                                           
                                        
        
                                                                        
        
                            
        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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