Product name: |
CHOP (2B1) Mouse mAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
GADD153, DDIT3,MGC4154 |
Source: |
Mouse |
Dilutions: |
WB? 1:1,000-2,000???? ?IHC 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Monoclonal |
Isotype: |
IgG1 |
Concentration: |
1mg/mL |
Observed Band: |
27kDa |
GeneID: |
1649 |
Human Swiss-Prot No: |
P35638 |
Cellular localization: |
Nucleus |
Background: |
CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase. |