Product name: |
Beclin-1 (5C2) Mouse mAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
ATG6, Bcl-2 interacting protein beclin, BECN1, Coiled coil myosin like BCL2 interacting protein |
Source: |
Mouse |
Dilutions: |
WB? 1:1,000-2,000???? IHC 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Monoclonal |
Isotype: |
IgG1 |
Concentration: |
1mg/mL |
Observed Band: |
60kDa |
GeneID: |
8678 |
Human Swiss-Prot No: |
Q14457 |
Cellular localization: |
Cytoplasm,?Cytoplasmic vesicle,?Endoplasmic reticulum,?Endosome,?Golgi apparatus,?Membrane,?Mitochondrion,?Nucleus |
Background: |
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1. |