| Product name: |
Fibronectin Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3 |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
285kDa |
| GeneID: |
2335 |
| Human Swiss-Prot No: |
P02751 |
| Cellular localization: |
Secreted, extracellular space, extracellular matrix |
| Background: |
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen.Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. |
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