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        CA IX/Carbonic Anhydrase IX Mouse mAb
        
                    EM1076
                    
        
                        
        
                            
        
                                規(guī)格：
                                價(jià)格：
                            
        
                                                        
        
                                50μL
                                ￥1280.00
                            
        
                                                        
        
                                100μL
                                ￥1980.00
                            
        
                                                    
        
                    
        
                    
                
        
            
        
        
        

                
        
            
        
                
        Overview
                    
        
                
        
                    
        
                        
        
                            
        
                                
        
                                    
        
                                        Product name:
                                        CA IX/Carbonic Anhydrase IX Mouse mAb
                                    
        
                                                                            
        
                                            Reactivity:
                                            Human
                                        
        
                                                                                
        
                                            Alternative Names:
                                            CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250
                                        
        
                                                                                
        
                                           Source:
                                           Mouse
                                           
                                        
        
                                                                                
        
                                           Dilutions:
                                           WB 1:3,000 IP 1:200? IHC 1:100-200
                                           
                                        
        
                                                                                
        
                                           Immunogen:
                                           Synthetic Peptide
                                           
                                        
        
                                                                                
        
                                           Storage:
                                           PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                                           
                                        
        
                                                                                
        
                                           Clonality:
                                           Monoclonal
                                           
                                        
        
                                                                                
        
                                           Isotype:
                                           IgG1
                                           
                                        
        
                                                                                
        
                                           Concentration:
                                           1mg/mL
                                           
                                        
        
                                                                                
        
                                           Observed Band:
                                           35-38kDa
                                           
                                        
        
                                                                                
        
                                           GeneID:
                                           768
                                           
                                        
        
                                                                                
        
                                           Human Swiss-Prot No:
                                           Q16790
                                           
                                        
        
                                                                                
        
                                           Cellular localization:
                                           Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.
                                           
                                        
        
                                                                                
        
                                           Background:
                                           The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.
                                           
                                        
        
                                                                        
        
                            
        
                                                    
        
                    
        
                
        
            
        
                        
                    
        
    
        
    




        
    
        
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