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EM1071

規(guī)格：	價(jià)格：
50μL	￥1280.00
100μL	￥1980.00

下載說(shuō)明 ①

Product name:	CD5 Mouse mAb
Reactivity:	Human, Rat, Mouse
Alternative Names:	CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1
Source:	Mouse
Dilutions:	IHC 1:100-200
Immunogen:	Synthetic Peptide
Storage:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:	Monoclonal
Isotype:	IgG1
Concentration:	1mg/mL
GeneID:	921
Human Swiss-Prot No:	P06127
Cellular localization:	Membrane
Background:	CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.