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        GFAP Mouse mAb
        EM1059
        規(guī)格: 價(jià)格:
        50μL ¥1280.00
        100μL ¥1980.00

        Overview

        Product name: GFAP Mouse mAb
        Reactivity: Rat, Mouse
        Alternative Names: Glial Fibrillary Acidic Protein ;Intermediate Filament Protein
        Source: Mouse
        Dilutions: WB 1:2,000-5,000 IHC 1:200-500
        Immunogen: Synthetic Peptide
        Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
        Clonality: Monoclonal
        Isotype: IgG1
        Concentration: 1mg/mL
        Observed Band: 45kDa
        GeneID: 2670
        Human Swiss-Prot No: P14136
        Cellular localization: Cytoplasm. Associated with intermediate filaments
        Background: GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
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