| Product name: |
p53 Mouse mAb |
| Reactivity: |
Human |
| Alternative Names: |
Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53 |
| Source: |
Mouse |
| Dilutions: |
WB 1:2,000 IHC 1:200 IF 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
53kDa |
| GeneID: |
7157 |
| Human Swiss-Prot No: |
P04637 |
| Cellular localization: |
Cytoplasm; Cytoplasm. Nucleus |
| Background: |
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. |
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