Product name: |
NBR1 Rabbit pAb |
Reactivity: |
Human, Mouse, Rat |
Alternative Names: |
1A13B, MIG19, Nbr1 |
Source: |
Rabbit |
Dilutions: |
IHC 1:100-200 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
120kDa |
GeneID: |
4077 |
Human Swiss-Prot No: |
Q14596 |
Cellular localization: |
Cytoplasm,?Cytoplasmic vesicle,?Lysosome |
Background: |
NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62. |