Product name: |
ATG13 Rabbit pAb |
Reactivity: |
Human, Mouse, Rat |
Alternative Names: |
KIAA0652,?Apg13,Autophagy-related protein 13 antibody |
Source: |
Rabbit |
Dilutions: |
IHC 1:100-200 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
57kDa |
GeneID: |
9776 |
Human Swiss-Prot No: |
O75143 |
Cellular localization: |
Cytoplasm |
Background: |
Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions. |