Product name: |
IkB α Rabbit pAb |
Reactivity: |
Human, Mouse, Rat |
Alternative Names: |
I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody |
Source: |
Rabbit |
Dilutions: |
WB 1:500-1,000? IHC 1:100-200 |
Immunogen: |
Recombinant Protein |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
40kDa |
GeneID: |
4792 |
Human Swiss-Prot No: |
P25963 |
Cellular localization: |
Cytoplasm,?Nucleus |
Background: |
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. |