Product name: |
KChIP1 Rabbit pAb |
Reactivity: |
Human, Mouse |
Alternative Names: |
KCNIP1,MGC9,MGC95,A type potassium channel modulatory protein 1 |
Source: |
Rabbit |
Dilutions: |
IHC 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
30kDa |
GeneID: |
30820 |
Human Swiss-Prot No: |
Q9NZI2 |
Cellular localization: |
Cell membrane,?Cell projection,?Cytoplasm,?Membrane |
Background: |
Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death. |